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Superficial thrombophlebitis of the penis.

What does penile Mondor’s disease look like?

It is a superficial thrombophlebitis or thrombosis of the dorsal vein of the penis.

Penile mondor’s disease causes

It usually occurs after prolonged and vigorous sexual activity. Damage to the wall of blood vessels occurs, resulting in impaired blood flow. Producing a vascular stasis (slow blood circulation) and in very rare cases hypercoagulability (excessive formation of blood clots) occurs.

This disease is NOT a sexually transmitted infection (STI). The main differential diagnosis of the disease is sclerosing lymphangitis (inflammation in the distal lymphatic vessels of the penis). It usually occurs in patients between the ages of 20 and 40.

Penile mondor’s disease diagnosis

  • Clinical History: Sudden history with the appearance of a swelling like a cord on the back of the shaft of the penis.
  • Doppler ultrasound (gold standard): Difference between Mondor disease of the penis and non-venereal sclerosing lymphangitis of the penis.

** Do not biopsy the skin of the penis.

Penile mondor’s disease symptoms

History of vigorous and prolonged sexual activity 24 to 48 hours before.
Palpable cord-like swelling; on the dorsal aspect of the distal shaft of the penis, in the middle of the shaft of the penis or extending to the base of the penis and the pubic region.
Pain that intensifies with erections, intercourse, or masturbation.
Erythema (redness of the skin).
Overlying edema.
Clinical presentation resolves in 4 to 8 weeks.

How is penile Mondor disease treated?

  • Refrain from sexual activity and sport until you have a complete resolution
  • Compresses with temperature changes (Hot / Cold) for pain relief.
  • Medicines:
    • Avoid anticoagulant therapy since they do not present any benefit.
    • Non-steroidal anti-inflammatory drugs that reduce the time of symptoms.

How do you get rid of Mondor’s disease?

Thrombectomy (surgery to remove a blood clot from inside an artery or vein): Recommended if the clot is persistent.


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